Darci Trader Lab
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Trader Lab Associations:
        -Purdue Center for Cancer Research
        -Purdue Institute for Drug Discovery
        -Purdue Institute for Integrative Neuroscience
        -PULSe Chemical Biology Training Group
         -Purdue T32 Drug Discovery and Infectious Disease                      Training Program

PI: Darci J. Trader

Darci received her BS and MS in chemistry from Southern Illinois University-Edwardsville in 2006 and 2007, respectively. She then went on to pursue her doctoral studies at Indiana University under the direction of Prof. Erin E. Carlson. Here, she worked on developing a new chemoselective enrichment tagging protocol to discover natural products.  After obtaining her PhD in 2013, she joined The Scripps Research Institute in Prof. Tom Kodadek's lab. At TSRI she learned to generate HTS libraries and screen them for the desired biological activity. Her own lab is focused the development of drug-like molecules and probes to monitor and perturb the activity of the proteasome. Small molecule probes, stimulators, and inhibitors are being generated to study the role of the standard proteasome and immunoproteasome in a variety of diseases. Her trainees are currently pursuing medicinal chemistry and chemical biology studies to develop new treatments for hematological cancers, proteasome stimulators to combat neurological diseases associated with protein accumulation, and new techniques to target the activity of the immunoproteasome.

Trader Laboratory PersonNel

Christine Muli

            Andres Salazar

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MCMP Graduate Student
​NIH F31-Fellow

B.S. Cal Poly, San Luis Obispo
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                MCMP Graduate Student

 Universidad Nacional de Colombia

KAte Kragness

Saayak Halder

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MCMP graduate student

B.S. Purdue University, Biochemistry
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                   Chemistry Graduate Student

B.S. University of Calcutta, India
​M.S. IIT Kanpur, India

Cody Loy

Tim Harris

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MCMP Graduate Student

B.S. Ball State, Chemistry
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MCMP Graduate Student

B.S. Rose-Hulman Institute of Technology, Biochemistry

Dr. Eslam Ali

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Postdoc

Ph.D., Korean Institute of Science and Technology, Chemistry

Alumni

Postdocs
Dr. Breanna Zerfas- Dana Farber, Research Scientist

Graduate Students
Dr. Marianne Maresh (Ph.D.) 2021- Postdoc at the University of Michigan
Dr. Wenzhi Tian (Ph.D.) 2021- Postdoc at the Broad Institute
Dr. Rachel Coleman (Ph.D.) 2020- Postdoc at UAB


Undergraduates
Nathan Macatangay (Undergraduate)- PharmD Student at Purdue
Brant Hoggatt (Undergraduate)
Brice Wuthrich (Undergraduate)- IU School of Medicine
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