Trader Lab Associations:
-Updating soon! |
PI: Darci J. TraderDarci received her BS and MS in chemistry from Southern Illinois University-Edwardsville in 2006 and 2007, respectively. She then went on to pursue her doctoral studies at Indiana University under the direction of Prof. Erin E. Carlson. Here, she worked on developing a new chemoselective enrichment tagging protocol to discover natural products. After obtaining her PhD in 2013, she joined The Scripps Research Institute in Prof. Tom Kodadek's lab. At TSRI she learned to generate HTS libraries and screen them for the desired biological activity. Her own lab is focused the development of drug-like molecules and probes to monitor and perturb the activity of the proteasome. Small molecule probes, stimulators, and inhibitors are being generated to study the role of the standard proteasome and immunoproteasome in a variety of diseases. Her trainees are currently pursuing medicinal chemistry and chemical biology studies to develop new treatments for hematological cancers, proteasome stimulators to combat neurological diseases associated with protein accumulation, and new techniques to target the activity of the immunoproteasome.
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Trader Laboratory PersonNel
Aron Weldai |
Andres Salazar |
Graduate StudenTB.S. Hampden-Sydney College
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MCMP Graduate Student Universidad Nacional de Colombia
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KAte Kragness |
Saayak Halder |
MCMP graduate studentB.S. Purdue University, Biochemistry
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Chemistry Graduate StudentB.S. University of Calcutta, India
M.S. IIT Kanpur, India |
Cody Loy |
Tim Harris |
MCMP Graduate StudentB.S. Ball State, Chemistry
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MCMP Graduate StudentB.S. Rose-Hulman Institute of Technology, Biochemistry
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Dr. Eslam Ali |
Duno Dantis |
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Postdoc |
UCI Chemistry graduate student |
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Ph.D., Korean Institute of Science and Technology, Chemistry
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B.S. University of the Philippines-Diliman, Chemistry
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Hanna King |
Jaida Osman |
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PULSE graduate student |
UCI Chemistry Graduate student |
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B.S. Purdue University, Biochemistry
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B.S. Cal State San Marcos, Biochemistry
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Alumni
Postdocs
Dr. Breanna Zerfas- Dana Farber, Research Scientist
Graduate Students
Dr. Christine Muli (Ph.D.) 2022- Postdoc at NIH-NCI
Dr. Marianne Maresh (Ph.D.) 2021- Postdoc at the University of Michigan
Dr. Wenzhi Tian (Ph.D.) 2021- Postdoc at the Broad Institute
Dr. Rachel Coleman (Ph.D.) 2020- Postdoc at UAB
Undergraduates
Nathan Macatangay (Undergraduate)- PharmD Student at Purdue
Brant Hoggatt (Undergraduate)
Brice Wuthrich (Undergraduate)- IU School of Medicine
Dr. Breanna Zerfas- Dana Farber, Research Scientist
Graduate Students
Dr. Christine Muli (Ph.D.) 2022- Postdoc at NIH-NCI
Dr. Marianne Maresh (Ph.D.) 2021- Postdoc at the University of Michigan
Dr. Wenzhi Tian (Ph.D.) 2021- Postdoc at the Broad Institute
Dr. Rachel Coleman (Ph.D.) 2020- Postdoc at UAB
Undergraduates
Nathan Macatangay (Undergraduate)- PharmD Student at Purdue
Brant Hoggatt (Undergraduate)
Brice Wuthrich (Undergraduate)- IU School of Medicine